Effects of Pera Orange Juice and Moro Orange Juice in Healthy Rats: A Metabolomic Approach.

ABSTRACT: Cardiovascular disease is a leading cause of death worldwide. Heart failure is a cardiovascular disease with high prevalence, morbidity, and mortality. Several natural compounds have been studied for attenuating pathological cardiac remodeling. Orange juice has been associated with cardiovascular disease prevention by attenuating oxidative stress. However, most studies have evaluated isolated phytochemicals rather than whole orange juice and usually under pathological conditions. In this study, we evaluated plasma metabolomics in healthy rats receiving Pera or Moro orange juice to identify possible metabolic pathways and their effects on the heart.

Methods

Sixty male Wistar rats were allocated into 3 groups: control (C), Pera orange juice (PO), and Moro orange juice (MO). PO and MO

SUBMITTER: Fujimori ASS 

PROVIDER: S-EPMC10456557 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature