Neutrophil CD64 index as a good biomarker for early diagnosis of bacterial infection in pregnant women during the flu season.

ABSTRACT:

Background

Pregnant women are at high risk of developing febrile illness during the flu season. Early identification of a viral or bacterial infection is crucial in the management of febrile pregnant patients. Neutrophil CD64 (nCD64) has been shown to have more important diagnostic value in sepsis than traditional inflammatory indicators.

Methods

The pregnant women enrolled were divided into three groups according to disease: influenza A infection, bacterial infection and healthy controls. Peripheral blood CD64, leukocyte, C-reactive protein (CRP), procalcitonin (PCT) and human Th1/Th2-related cytokines levels were routinely measured. The correlation between and diagnostic value of the nCD64 index and other biomarkers were evaluated using Spearman's correlation test and rece

SUBMITTER: Yu L 

PROVIDER: S-EPMC10457501 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature