Exploring Shigella vaccine priorities and preferences: Results from a mixed-methods study in low- and middle-income settings

ABSTRACT: Highlights • High Shigella awareness but low vaccine interest due to low perceived burden and crowded schedule.• Shigella vaccine priority increased if impacts on stunting and antimicrobial resistance included.• Strong stakeholder preference for oral and combination vaccine formulations.

Background

Shigella is the leading bacterial cause of diarrheal mortality in children and can cause long-term effects on growth and development. No licensed Shigella vaccines currently exist but several promising candidates are in development and could be available in the next five years. Despite Shigella being a well-known public health target of the World Health Organization for decades, given current burden estimates and competing preventable disease priorities in low-income settings, whether t

SUBMITTER: Fleming J 

PROVIDER: S-EPMC10457597 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature