Constructing ROS-Responsive Supramolecular Gel with Innate Antibacterial Properties.

ABSTRACT: Bacterial infections, especially antibiotic-resistant bacterial infections, pose a significant threat to human health. Supramolecular gel with innate antibacterial properties is an advanced material for the treatment of bacterial infections, which have attracted great attention. Herein, a reactive oxygen species (ROS)-responsive innate antibacterial supramolecular gel is developed by a bottom-up approach based on phenylalanine and hydrazide with innate antibacterial properties. The structure of gelators and intermediate products was characterized by proton nuclear magnetic resonance (¹H NMR) and a high-resolution mass spectrum (HRMS). The results of ¹H NMR and the Fourier transform infrared spectrum (FT-IR) experiment disclosed that hydrogen bonding and the π-π stacki

SUBMITTER: Zheng F 

PROVIDER: S-EPMC10458117 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature