Hydrothermal Transformation of Eggshell Calcium Carbonate into Apatite Micro-Nanoparticles: Cytocompatibility and Osteoinductive Properties.

ABSTRACT: The eggshell is a biomineral consisting of CaCO₃ in the form of calcite phase and a pervading organic matrix (1-3.5 wt.%). Transforming eggshell calcite particles into calcium phosphate (apatite) micro-nanoparticles opens the door to repurposing the eggshell waste as materials with potential biomedical applications, fulfilling the principles of the circular economy. Previous methods to obtain these particles consisted mainly of two steps, the first one involving the calcination of the eggshell. In this research, direct transformation by a one-pot hydrothermal method ranging from 100-200 °C was studied, using suspensions with a stoichiometric P/CaCO₃ ratio, K₂HPO₄ as P reagent, and eggshells particles (Ø < 50 μm) both untreated and treated with Na

SUBMITTER: Torres-Mansilla A 

PROVIDER: S-EPMC10458568 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature