Induced Vascular Normalization-Can One Force Tumors to Surrender to a Better Microenvironment?

ABSTRACT: Immunotherapy has changed the way many cancers are being treated. Researchers in the field of immunotherapy and tumor immunology are investigating similar questions: How can the positive benefits achieved with immunotherapies be enhanced? Can this be achieved through combinations with other agents and if so, which ones? In our view, there is an urgent need to improve immunotherapy to make further gains in the overall survival for those patients that should benefit from immunotherapy. While numerous different approaches are being considered, our team believes that drug delivery methods along with appropriately selected small-molecule drugs and drug candidates could help reach the goal of doubling the overall survival rate that is seen in some patients that are given immunotherapeutics. This

SUBMITTER: Sun XX 

PROVIDER: S-EPMC10458586 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature