International Clones of High Risk of Acinetobacter Baumannii-Definitions, History, Properties and Perspectives.

ABSTRACT: Acinetobacter baumannii is a Gram-negative coccobacillus with exceptional survival skills in an unfavorable environment and the ability to rapidly acquire antibiotic resistance, making it one of the most successful hospital pathogens worldwide, representing a serious threat to public health. The global dissemination of A. baumannii is driven by several lineages named 'international clones of high risk' (ICs), two of which were first revealed in the 1970s. Epidemiological surveillance is a crucial tool for controlling the spread of this pathogen, which currently increasingly involves whole genome sequencing. However, the assignment of a particular A. baumannii isolate to some IC based on its genomic sequence is not always straightforward and requires some computational

SUBMITTER: Shelenkov A 

PROVIDER: S-EPMC10459012 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature