Just Keep Rolling?-An Encompassing Review towards Accelerated Vaccine Product Life Cycles.

ABSTRACT: In light of the recent pandemic, several COVID-19 vaccines were developed, tested and approved in a very short time, a process that otherwise takes many years. Above all, these efforts have also unmistakably revealed the capacity limits and potential for improvement in vaccine production. This review aims to emphasize recent approaches for the targeted rapid adaptation and production of vaccines from an interdisciplinary, multifaceted perspective. Using research from the literature, stakeholder analysis and a value proposition canvas, we reviewed technological innovations on the pharmacological level, formulation, validation and resilient vaccine production to supply bottlenecks and logistic networks. We identified four main drivers to accelerate the vaccine product life cycle: computerize

SUBMITTER: Stiefel J 

PROVIDER: S-EPMC10459022 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature