Treating Epilepsy with Natural Products: Nonsense or Possibility?

ABSTRACT: Epilepsy is a neurological disease characterized by recurrent seizures that can lead to uncontrollable muscle twitching, changes in sensitivity to sensory perceptions, and disorders of consciousness. Although modern medicine has effective antiepileptic drugs, the need for accessible and cost-effective medication is urgent, and products derived from plants could offer a solution. For this review, we have focused on natural compounds that have shown anticonvulsant activity in in vivo models of epilepsy at relevant doses. In some cases, the effects have been confirmed by clinical data. The results of our search are summarized in tables according to their molecular targets. We have critically evaluated the data we present, identified the most promising therapeutic candidates, and discussed the

SUBMITTER: Malanik M 

PROVIDER: S-EPMC10459181 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature