Sex- and Age-Dependent Associations between Parabacteroides and Obesity: Evidence from Two Population Cohort.

ABSTRACT: Parabacteroides levels are reported to be low in obese individuals, and this genus has shown an anti-obesity capacity in animal studies. Nevertheless, the relationship between Parabacteroides and obesity in different subpopulations, e.g., with respect to age and sex, and its association with subsequent weight change have rarely been explored. The cross-sectional associations of Parabacteroides genus- and species-level OTU abundance with obesity were explored in the Guangdong Gut Microbiome Project (GGMP), which included 5843 adults, and replicated in the Guangzhou Nutrition and Health Study (GNSH), which included 1637 individuals. Furthermore, we assessed the prospective associations of Parabacteroides and its main OTUs' abundance with the subseque

SUBMITTER: Zhang F 

PROVIDER: S-EPMC10459623 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature