Antiviral Activities of Streptomyces KSF 103 Methanolic Extracts against Dengue Virus Type-2.

ABSTRACT: Dengue has long been a serious health burden to the global community, especially for those living in the tropics. Despite the availability of vaccines, effective treatment for the infection is still needed and currently remains absent. In the present study, the antiviral properties of the Streptomyces sp. KSF 103 methanolic extract (Streptomyces KSF 103 ME), which consists of a number of potential antiviral compounds, were investigated against dengue virus serotype 2 (DENV-2). The effects of this extract against DENV-2 replication were determined using the quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). Findings from the study suggested that the Streptomyces KSF 103 ME showed maximum inhibitory properties toward the virus during the virus entry stage at con

SUBMITTER: Zulkifli N 

PROVIDER: S-EPMC10459629 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature