Efficacy of osteoporosis pharmacological treatments in men: a systematic review and meta-analysis.

ABSTRACT:

Introduction

The objective of this systematic review and meta-analysis is to systematically identify and review the efficacy of pharmacological treatments in men with osteoporosis.

Methods

Medline (via Ovid) and Cochrane CENTRAL were searched up to May 2023 for any randomized controlled trial (RCT) evaluating the efficacy of osteoporotic treatment on the evolution of Bone Mineral Density (BMD) and incidence of fractures of men suffering from primary osteoporosis. If at least two studies used the same pharmacological treatment and evaluated the same outcome, a random effect model meta-analysis was applied to reported pooled mean difference (MD) and 95% confidence interval (CI).

Results

From the 1,061 studies identified through bibliographic search, 21 RCTs fitted the i

SUBMITTER: Beaudart C 

PROVIDER: S-EPMC10460304 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature