Multiplex core of the human brain using structural, functional and metabolic connectivity derived from hybrid PET-MR imaging.

ABSTRACT: With the increasing success of mapping brain networks and availability of multiple MR- and PET-based connectivity measures, the need for novel methodologies to unravel the structure and function of the brain at multiple spatial and temporal scales is emerging. Therefore, in this work, we used hybrid PET-MR data of healthy volunteers (n = 67) to identify multiplex core nodes in the human brain. First, monoplex networks of structural, functional and metabolic connectivity were constructed, and consequently combined into a multiplex SC-FC-MC network by linking the same nodes categorically across layers. Taking into account the multiplex nature using a tensorial approach, we identified a set of core nodes in this multiplex network based on a combination of eigentensor centrality and ove

SUBMITTER: Devrome M 

PROVIDER: S-EPMC10461102 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature