Hepcidin across pregnancy and its correlation with maternal markers of iron and inflammation, maternal body weight outcomes, and offspring neurodevelopmental outcomes: a systematic review and meta-analysis.

ABSTRACT:

Objective

This study evaluated the correlation between maternal hepcidin and other biomarkers of iron status, markers of inflammation, and maternal body weight during pregnancy, as well as neurodevelopment in the offspring.

Data sources

PubMed, Web of Science, Scopus, and Embase were searched from inception until March 2022.

Study eligibility criteria

Studies conducted among pregnant women without apparent pregnancy complications were included. Eligible studies reported correlation coefficients between maternal hepcidin and any outcomes of maternal biomarkers of iron status or inflammatory load during pregnancy, prenatal maternal body weight, and offspring neurodevelopment. Studies without correlation data were eligible if they quantitatively reported volumes of both

SUBMITTER: Ssewanyana D 

PROVIDER: S-EPMC10461250 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature