Evaluation of tumour motion and internal/external correlation in lung SABR.

ABSTRACT:

Objective

This study aims to analyse lung tumour motion and to investigate the correlation between the internal tumour motion acquired from four-dimensional computed tomography (4DCT) and the motion of an external surrogate.

Methods

A data set of 363 4DCT images was analysed. Tumours were classified based on their anatomical lobes. The recorded gross tumour volume (GTV) information included the centroid GTV motion in the superior-inferior, anteroposterior and left-right directions, and in three-dimensions (3D). For the internal/external correlation, the RPM surrogate breathing signals of 260 patients were analysed via an in-house script. The external motion was correlated with the 3D centroid motion, and the maximum tumour motion via Spearman's correlation. The effect of tum

SUBMITTER: Ali AM 

PROVIDER: S-EPMC10461274 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature