Neurological Impairment in Critically Ill Patients on Dialysis: Research Letter for the INCOGNITO-AKI Feasibility Study.

ABSTRACT:

Background

Acute kidney injury (AKI) resulting in kidney replacement therapy is rising among critically ill adults. Long-term kidney replacement therapy and critical illness are independently linked to acute and prolonged cognitive impairment, and structural brain pathology. Poor regional cerebral oxygenation (rSO₂) may be a contributing factor.

Objective

To assess the feasibility of testing the association between intradialytic rSO₂ and acute and long-term neurological outcomes.

Design

Longitudinal observational study.

Setting and participants

We enrolled patients initiating continuous kidney replacement therapy or intermittent hemodialysis in the Kingston Health Sciences Centre (KHSC) Intensive Care Unit (ICU).

Measurements and method

SUBMITTER: Jawa NA 

PROVIDER: S-EPMC10461308 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature