Coherent feedback leads to robust background compensation in oscillatory and non-oscillatory homeostats.

ABSTRACT: When in a reaction kinetic integral controller a step perturbation is applied besides a constant background, the concentration of a controlled variable (described as A) will generally respond with decreased response amplitudes ΔA as backgrounds increase. The controller variable E will at the same time provide the necessary compensatory flux to move A back to its set-point. A typical example of decreased response amplitudes at increased backgrounds is found in retinal light adaptation. Due to remarks in the literature that retinal light adaptation would also involve a compensation of backgrounds we became interested in conditions how background compensation could occur. In this paper we describe novel findings how background influences can be robustly eliminated. When such a background comp

SUBMITTER: Nygard M 

PROVIDER: S-EPMC10461855 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature