Ontology highlight
ABSTRACT:
SUBMITTER: Ahmed YM
PROVIDER: S-EPMC10462113 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Ahmed Yasin M YM Bowman Grant R GR
bioRxiv : the preprint server for biology 20230820
Asymmetric cell division in bacteria is achieved through cell polarization, where regulatory proteins are directed to specific cell poles. Curiously, both poles contain a membraneless microdomain, established by the polar assembly hub PopZ, through most of the cell cycle, yet many PopZ clients are unipolar and transiently localized. We find that PopZ's interaction with the response regulator CpdR is controlled by phosphorylation, via the histidine kinase CckA. Phosphorylated CpdR does not intera ...[more]