Determinants of Gastrointestinal Group B Streptococcus Carriage in Adults.

ABSTRACT:

Background

Streptococcus agalactiae (Group B Streptococcus, GBS) is a commensal Gram-positive bacterium found in the human gastrointestinal and urogenital tracts. Much of what is known about GBS relates to the diseases it causes in pregnant people and neonates. However, GBS is a common cause of disease in the general population with 90% of GBS mortality occurring in non-pregnant people. There are limited data about the predisposing factors for GBS and the reservoirs in the body. To gain an understanding of the determinants of gastrointestinal GBS carriage, we used stool samples and associated metadata to determine the prevalence and abundance of GBS in the gut microbiome of adults and find risk factors for GBS status.

Methods

We used 754 stool samples collected

SUBMITTER: Cowley ES 

PROVIDER: S-EPMC10462156 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature