Base Composition, Codon Usage, and Patterns of Gene Sequence Evolution in Butterflies.

ABSTRACT: Coding sequence evolution is influenced by both natural selection and neutral evolutionary forces. In many species, the effects of mutation bias, codon usage, and GC-biased gene conversion (gBGC) on gene sequence evolution have not been detailed. Quantification of how these forces shape substitution patterns is therefore necessary to understand the strength and direction of natural selection. Here, we used comparative genomics to investigate the association between base composition and codon usage bias on gene sequence evolution in butterflies and moths (Lepidoptera), including an in-depth analysis of underlying patterns and processes in one species, Leptidea sinapis. The data revealed significant G/C to A/T substitution bias at third codon position with some variation in the strength amon

SUBMITTER: Nasvall K 

PROVIDER: S-EPMC10462419 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature