Long-term follow up of patients with WHO grade 2 oligodendroglioma.

ABSTRACT:

Purpose

Since the introduction of the molecular definition of oligodendrogliomas based on isocitrate dehydrogenase (IDH)-status and the 1p19q-codeletion, it has become increasingly evident how this glioma entity differs much from other diffuse lower grade gliomas and stands out with longer survival and often better responsiveness to adjuvant therapy. Therefore, apart from using a molecular oligodendroglioma definition, an extended follow-up time is necessary to understand the nature of this slow growing, yet malignant condition. The aim of this study was to describe the long-term course of the oligodendroglioma disease in a population-based setting and to determine which factors affect outcome in terms of survival.

Methods

All adults with WHO-grade 2 oligodendrogliomas with

SUBMITTER: Carstam L 

PROVIDER: S-EPMC10462563 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature