Real-world clinical practice of pulmonary arterial hypertension in Japan: Insights from a large administrative database.

ABSTRACT: Pulmonary arterial hypertension (PAH) is a fatal disease that often occurs at an early age. In recent years, aggressive treatment with multiple drugs from the early-stage diagnosis is expected to improve the prognosis. Indeed, a high rate of initial combination therapy and excellent treatment outcomes have been reported from specialized centers for PAH in Japan. However, information on PAH epidemiology, including non-PAH specialized centers in Japan, is unclear. To address the above, we conducted a retrospective observational cohort study from April 2008 to September 2020 using real-world evidence from a large-scale administrative database (Medical Data Vision) to examine baseline characteristics, comorbidities, and treatment profiles of Japanese patients with PAH. Five hundred and eightee

SUBMITTER: Omura J 

PROVIDER: S-EPMC10462924 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature