Association between history of cholecystectomy and risk of gastric cancer: a meta-analysis of epidemiological studies.

ABSTRACT:

Purpose

Evidence from previous studies on the association between cholecystectomy and risk of gastric cancer are still inconsistent. We aimed at conducting a meta-analysis of epidemiological studies to evaluate this association.

Methods

Researchers searched three databases (PubMed, Embase and Web of Science) through January 2021 for eligible studies. Relative risks (RRs) and 95% CIs in each included studies were pooled by random-effects models. Patients and the public were not involved in our study.

Results

Eight studies were identified. Four studies reported significantly positive association between history of cholecystectomy and risk of gastric cancer, and the remaining studies reported null association. The pooled RR of these eight studies showed that a history of

SUBMITTER: Sun M 

PROVIDER: S-EPMC10462960 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature