The impact of emphysema heterogeneity on treatment response after endobronchial valve treatment.

ABSTRACT:

Background

Lung volume reduction with endobronchial valves can significantly improve functional outcomes in patients with advanced emphysema. The extent and spatial distribution pattern of emphysema shows considerable heterogeneity, which might affect response to endobronchial valve treatment. Our aim was to study the effect of emphysema heterogeneity on change in clinical outcomes after endobronchial valve treatment.

Methods

Data were collected from our national registry of patients who received endobronchial valve treatment between 2016 and 2020. We assessed the association between the heterogeneity index, absolute difference in destruction between the target and ipsilateral lobe, and relative change in forced expiratory volume in 1 s (FEV₁), residual volume (RV

SUBMITTER: Roodenburg SA 

PROVIDER: S-EPMC10463031 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature