Projected Outcomes of Optimized Statin and Ezetimibe Therapy in US Military Veterans with Coronary Artery Disease.

ABSTRACT:

Importance

Many patients with coronary artery disease (CAD) do not achieve the guideline-directed goals for low-density lipoprotein cholesterol (LDL-C) levels.

Objective

To estimate reductions in the rates of adverse events associated with CAD in a large US military veteran population that may be achieved through use of optimized statin therapy alone or with ezetimibe compared with the prevailing lipid-lowering therapy (LLT).

Design, setting, and participants

In this observational cohort study, US military veterans with CAD were identified by coronary angiography between June 2015 and September 2020 across 82 US Department of Veterans Affairs health care facilities.

Exposures

The exposures were observed LLT, LLT with an optimized statin regimen, and LLT with op

SUBMITTER: Kovach CP 

PROVIDER: S-EPMC10463102 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature