Sleep Disturbances Predict Cognitive Decline in Cognitively Healthy Adults.

ABSTRACT:

Background

The effect of nighttime behaviors on cognition has not been studied independently from other neuropsychiatric symptoms.

Objective

We evaluate the following hypotheses that sleep disturbances bring increased risk of earlier cognitive impairment, and more importantly that the effect of sleep disturbances is independent from other neuropsychiatric symptoms that may herald dementia.

Methods

We used the National Alzheimer's Coordinating Center database to evaluate the relationship between Neuropsychiatric Inventory Questionnaire (NPI-Q) determined nighttime behaviors which served as surrogate for sleep disturbances and cognitive impairment. Montreal Cognitive Assessment scores defined two groups: conversion from 1) normal to mild cognitive impairment (MCI) and 2

SUBMITTER: Zawar I 

PROVIDER: S-EPMC10463264 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature