Multivariate genome-wide associations for immune traits in two maternal pig lines.

ABSTRACT:

Background

Immune traits are considered to serve as potential biomarkers for pig's health. Medium to high heritabilities have been observed for some of the immune traits suggesting genetic variability of these phenotypes. Consideration of previously established genetic correlations between immune traits can be used to identify pleiotropic genetic markers. Therefore, genome-wide association study (GWAS) approaches are required to explore the joint genetic foundation for health biomarkers. Usually, GWAS explores phenotypes in a univariate (uv), trait-by-trait manner. Besides two uv GWAS methods, four multivariate (mv) GWAS approaches were applied on combinations out of 22 immune traits for Landrace (LR) and Large White (LW) pig lines.

Results

In total 433 (LR: 351, LW: 82) ass

SUBMITTER: Roth K 

PROVIDER: S-EPMC10463314 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature