Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease.

ABSTRACT:

Background

Kikuchi-Fujimoto disease (KFD) is typically a benign, self-limiting inflammatory disease. The diagnosis of KFD can be challenging for nonspecific symptoms, laboratory or imaging findings. In this study, we aimed to describe the clinical manifestations of patients with KFD and to access the potential role of serum cytokines in the diagnosis of this disease.

Methods

Patients with KFD were retrospectively enrolled from January 2015 to November 2021 at Shenzhen Children's Hospital. Clinical data were collected from inpatient or outpatient medical records. Serum cytokines were detected by the Flowcytomix technique. Serum levels of cytokines were compared between patients with KFD and SJIA, or patients with KFD and KD. The data of patients without MAS were further analy

SUBMITTER: He T 

PROVIDER: S-EPMC10463342 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature