Prevalence of subclinical lung cancer detected at autopsy: a systematic review.

ABSTRACT:

Background

Lung cancer screening in high-risk populations with low-dose computed tomography is supported by international associations and recommendations. Overdiagnosis is considered a risk of screening with associated harms. The aim of this paper is to determine the prevalence of subclinical lung cancer diagnosed post-mortem to better understand the reservoir of subclinical lung cancer.

Methods

We searched EMBASE, PubMed, and MEDLINE databases from inception until March 2022 with no language restrictions. We considered all studies with ≥100 autopsies in adults. Two reviewers independently assessed eligibility of studies, extracted data, and assessed risk of bias of included studies. We performed a meta-analysis using a random-effects model for prevalence of subclinical lun

SUBMITTER: Bonney A 

PROVIDER: S-EPMC10463584 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature