Benefits of near-universal vaccination and treatment access to manage COVID-19 burden in the United States.

ABSTRACT:

Background

As we continue the fourth year of the COVID-19 epidemic, SARS-CoV-2 infections still cause high morbidity and mortality in the United States. During 2020-2022, COVID-19 was one of the leading causes of death in the United States and by far the leading cause among infectious diseases. Vaccination uptake remains low despite this being an effective burden reducing intervention. The development of COVID-19 therapeutics provides hope for mitigating severe clinical outcomes. This modeling study examines combined strategies of vaccination and treatment to reduce the burden of COVID-19 epidemics over the next decade.

Methods

We use a validated mathematical model to evaluate the reduction of incident cases, hospitalized cases, and deaths in the United States through 2033 u

SUBMITTER: Yang F 

PROVIDER: S-EPMC10463609 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature