Alcohol exposure before and during pregnancy is associated with reduced fetal growth: the Safe Passage Study.

ABSTRACT:

Background

Prenatal alcohol exposure (PAE) is a worldwide public health concern. While PAE is known to be associated with low birth weight, little is known about timing and quantity of PAE on fetal growth. This study investigated the association between periconceptional and prenatal alcohol exposure and longitudinal fetal growth, focusing on timing and quantity in a high exposure cohort.

Methods

The Safe Passage Study was a prospective cohort study, including 1698 pregnant women. Two-dimensional transabdominal ultrasound examinations were performed to measure fetal femur length, abdominal and head circumference, and biparietal diameter, at three time points during pregnancy. Estimated fetal weight and Z-scores of all parameters were calculated. Trimester-specific alcohol exp

SUBMITTER: Pielage M 

PROVIDER: S-EPMC10463675 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature