Early life stress, prenatal secondhand smoke exposure, and the development of internalizing symptoms across childhood.

ABSTRACT:

Background

Prior findings relating secondhand tobacco smoke (SHS) exposure and internalizing problems, characterized by heightened anxiety and depression symptoms, have been equivocal; effects of SHS on neurodevelopment may depend on the presence of other neurotoxicants. Early life stress (ELS) is a known risk factor for internalizing symptoms and is also often concurrent with SHS exposure. To date the interactive effects of ELS and SHS on children's internalizing symptoms are unknown. We hypothesize that children with higher exposure to both prenatal SHS and ELS will have the most internalizing symptoms during the preschool period and the slowest reductions in symptoms over time.

Methods

The present study leveraged a prospective, longitudinal birth cohort of 564 Black and L

SUBMITTER: DeSerisy M 

PROVIDER: S-EPMC10463722 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature