Ontology highlight
ABSTRACT: Background
Cancers are as common in individuals with intellectual disabilities as in the general population (GP). For the subgroup of people with profound and multiple disabilities (PMD) who present with both severe intellectual disability and major motor disorders, the frequency and distribution of cancers are currently not known, preventing proper cancer surveillance.Methods
We carried out a systematic and synthetic review of the medical literature, including a focused search of Japanese data.Results
The total risk of cancer in individuals with PMD is thought to be lower than in the GP, possibly due to a shorter life expectancy. They have reduced exposure to cancer risk factors, such as alcohol, tobacco, sunlight, human papillomavirus infection, occupational toxin
SUBMITTER: Satge D
PROVIDER: S-EPMC10463777 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature