Clinical burden of invasive Escherichia coli disease among older adult patients treated in hospitals in the United States.

ABSTRACT:

Background

Invasive extraintestinal pathogenic Escherichia coli disease (IED) can lead to severe outcomes, particularly among older adults. However, the clinical burden of IED in the U.S. has not been well characterized.

Methods

IED encounters among patients ≥ 60 years old were identified using the PINC AI™ Healthcare Database (10/01/2015-03/31/2020) by either a positive E. coli culture in blood or another normally sterile body site and ≥ 1 sign of systemic inflammatory response syndrome or signs of sepsis, or a positive E. coli culture in urine with urinary tract infection and signs of sepsis. Medical resource utilization, clinical outcomes, and E. coli isolate characteristics were descriptively reported during the first IED encounter and during the following year (observat

SUBMITTER: Hernandez-Pastor L 

PROVIDER: S-EPMC10464165 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature