Clinical practice of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease.

ABSTRACT:

Background

Non-invasive ventilation (NIV) is an evidence-based treatment for acute respiratory failure in chronic obstructive pulmonary disease (COPD). However, suboptimal application of NIV in clinical practice, possibly due to poor guideline adherence, can impact patient outcomes. This study aims to evaluate guideline adherence to NIV for acute COPD exacerbations and explore its impact on mortality.

Methods

This retrospective study was performed in two Dutch medical centers from 2019 to 2021. All patients admitted to the pulmonary ward or intensive care unit with a COPD exacerbation were included. An indication for NIV was considered in the event of a respiratory acidosis.

Results

A total of 1162 admissions (668 unique patients) were included. NIV was started in 154

SUBMITTER: Elshof J 

PROVIDER: S-EPMC10464197 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature