Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database.

ABSTRACT: Previous studies have shown that associations between obesity and other comorbidities favor worse outcomes in COVID-19. However, it is not clear how these factors interrelate and whether effects on men and women differ. We conducted an observational, cross-sectional study using a national COVID-19 inpatient database. We studied differences in direct and indirect effects of obesity and comorbidities according to sex and body mass index (BMI) categories in hospitalized COVID-19 patients in Brazil using path analysis models and logistic regression. For men, path analysis showed a direct association between BMI and death and a negative correlation of death and chronic cardiovascular disease (CCD). For women, the association of BMI and death was indirect, mediated by admission to the ICU and co

SUBMITTER: Dos Reis EC 

PROVIDER: S-EPMC10464316 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature