Severe falciparum malaria in pregnancy in Southeast Asia: a multi-centre retrospective cohort study.

ABSTRACT:

Background

Severe malaria in pregnancy causes maternal mortality, morbidity, and adverse foetal outcomes. The factors contributing to adverse maternal and foetal outcomes are not well defined. We aimed to identify the factors predicting higher maternal mortality and to describe the foetal mortality and morbidity associated with severe falciparum malaria in pregnancy.

Methods

A retrospective cohort study was conducted of severe falciparum malaria in pregnancy, as defined by the World Health Organization severe malaria criteria. The patients were managed prospectively by the Shoklo Malaria Research Unit (SMRU) on the Thailand-Myanmar border or were included in hospital-based clinical trials in six Southeast Asian countries. Fixed-effects multivariable penalised logistic regres

SUBMITTER: Saito M 

PROVIDER: S-EPMC10464355 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature