Liposomal delivery of gene therapy for ovarian cancer: a systematic review.

ABSTRACT:

Objective

To systematically identify and narratively synthesize the evidence surrounding liposomal delivery of gene therapy and the outcome for ovarian cancer.

Methods

An electronic database search of the Embase, MEDLINE and Web of Science from inception until July 7, 2023, was conducted to identify primary studies that investigated the effect of liposomal delivery of gene therapy on ovarian cancer outcomes. Retrieved studies were assessed against the eligibility criteria for inclusion.

Results

The search yielded 564 studies, of which 75 met the inclusion criteria. Four major types of liposomes were identified: cationic, neutral, polymer-coated, and ligand-targeted liposomes. The liposome with the most evidence involved cationic liposomes which are characterized by th

SUBMITTER: Son JS 

PROVIDER: S-EPMC10464441 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature