Characterizations of bla_CTX-M-14 and bla_CTX-M-64 in a clinical isolate of Escherichia coli from China.

ABSTRACT: Extended-spectrum beta-lactamase-producing Gram-negative bacteria are common in the community and hospitals. To monitor ESBLs mediated by the CTX-M genotype, we collected clinical ESBL pathogenic strains from a hospital in central China and observed a strain of Escherichia coli, namely Ec15103 carrying bla_CTX-M-14, bla_CTX-M-64 and bla_TEM-1, isolated from the blood of a 7-day-old infant in 2015. Strain Ec15103 contains two drug resistance plasmids: pEc15103A, an IncFI-type plasmid that cannot be conjugatively transferred and carries the drug resistance genes bla_TEM-1, aacC2, aadA5, sul1, mph(A), sul2, strAB, and tetA(A); and pEc15103B, an IncK2/Z-type plasmid that

SUBMITTER: Yang M 

PROVIDER: S-EPMC10464524 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature