Association between constipation and major depression in adult Americans: evidence from NHANES 2005–2010

ABSTRACT:

Objective

Current studies on the association between constipation and depression is still insufficient. In this study, we investigated the detailed association between constipation and major depression among American adults.

Methods

In this cross-sectional study, 12,352 adults aged 20 and older were selected from the National Health and Nutrition Examination Survey 2005–2010 for the sample. Constipation was defined as fewer than three defecation frequencies per week. For the assessment of major depression, the validated Patient Health Questionnaire-9 was used. Adjusted odds ratios (ORs) were calculated using multivariate logistic regression models. A subgroup analysis was carried out to ensure that the results were stable.

Results

Of the 12,352 participants, 430

SUBMITTER: Wang P 

PROVIDER: S-EPMC10465693 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature