Anti-cancer activity of C. cainito leaves explained using its compounds docked with p53.

ABSTRACT: Extensive research on the mutant P53 protein has identified its pivotal role in anti-apoptosis mechanisms, drug resistance, and cancer progression in OSCC. The mass spectrum revealed the pharmacologically significant bioactive compounds reported for the first time in C cainito. Molecular docking investigation has identified four potential new P53 inhibitors compared with the standard P53 inhibitors. Hence, this analysis reinforces the likelihood of anti-cancer activities in C. cainito leaves.

SUBMITTER: Prabhu YA 

PROVIDER: S-EPMC10465767 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature