Transcriptomic signature related to poor welfare of sport horses.

ABSTRACT: The improvement of horse welfare through housing conditions has become a real issue in recent years and have highlighted the detrimental effect of individual housing of horses on their health and behaviour. In this new study, we analysed the blood transcriptome of 45 sport horses housed individually that were previously examined for their behaviour and gut microbiota. We performed differential and regression analyses of gene expression, followed by downstream bioinformatic analyses, to unveil the molecular pathways related to the behavioural changes associated with welfare impairment in these sport horses. We found that aggressiveness towards humans was the behavioural indicator the most correlated to blood gene expression and that the pathways involved belonged mainly to systemic inflamma

SUBMITTER: Foury A 

PROVIDER: S-EPMC10465861 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature