Association between carotid atherosclerosis and brain activation patterns during the Stroop task in older adults: An fNIRS investigation.

ABSTRACT: There is an increasing body of evidence suggesting that vascular disease could contribute to cognitive decline and overt dementia. Of particular interest is atherosclerosis, as it is not only associated with dementia, but could be a potential mechanism through which cardiovascular disease directly impacts brain health. In this work, we evaluated the differences in functional near infrared spectroscopy (fNIRS)-based measures of brain activation, task performance, and the change in central hemodynamics (mean arterial pressure (MAP) and heart rate (HR)) during a Stroop color-word task in individuals with atherosclerosis, defined as bilateral carotid plaques (n = 33) and healthy age-matched controls (n = 33). In the healthy control group, the left prefrontal cortex (LPFC) was the only region s

SUBMITTER: Mason SA 

PROVIDER: S-EPMC10466022 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature