Trends in Photopolymerizable Bioinks for 3D Bioprinting of Tumor Models.

ABSTRACT: Three-dimensional (3D) bioprinting technologies involving photopolymerizable bioinks (PBs) have attracted enormous attention in recent times owing to their ability to recreate complex structures with high resolution, mechanical stability, and favorable printing conditions that are suited for encapsulating cells. 3D bioprinted tissue constructs involving PBs can offer better insights into the tumor microenvironment and offer platforms for drug screening to advance cancer research. These bioinks enable the incorporation of physiologically relevant cell densities, tissue-mimetic stiffness, and vascularized channels and biochemical gradients in the 3D tumor models, unlike conventional two-dimensional (2D) cultures or other 3D scaffold fabrication technologies. In this perspective, we present t

SUBMITTER: Gugulothu SB 

PROVIDER: S-EPMC10466332 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature