Genomic and metabonomic methods reveal the probiotic functions of swine-derived Ligilactobacillus salivarius.

ABSTRACT:

Background

As substitutes for antibiotics, probiotic bacteria protect against digestive infections caused by pathogenic bacteria. Ligilactobacillus salivarius is a species of native lactobacillus found in both humans and animals. Herein, a swine-derived Ligilactobacillus salivarius was isolated and shown to colonize the ileal mucous membrane, thereby promoting nutritional digestion, absorption, and immunity. To evaluate its probiotic role, the entire genome was sequenced, the genetic information was annotated, and the metabolic information was analyzed.

Results

The phylogenetic relationship indicated that the bacteria was closer to L. salivarius MT573555.1 and MT585431.1. Functional genes included transporters, membrane proteins, enzymes, heavy metal resistance proteins, and

SUBMITTER: Yang J 

PROVIDER: S-EPMC10466738 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature