Ontology highlight
ABSTRACT: Background
Sedentary lifestyle and unhealthy diet combined with overweight are risk factors for type 2 diabetes (T2D). Lifestyle interventions with weight-loss are effective in T2D-prevention, but unsuccessful completion and chronic stress may hinder efficacy. Determinants of chronic stress and premature cessation at the start of the 3-year PREVIEW study were examined.Methods
Baseline Quality of Life (QoL), social support, primary care utilization, and mood were examined as predictors of intervention cessation and chronic stress for participants aged 25 to 70 with prediabetes (n = 2,220). Moderating effects of sex and socio-economic status (SES) and independence of predictor variables of BMI were tested.Results
Participants with children, women, and higher SES quitted intervention earlier than those without children, lower SES, and men. Lower QoL, lack of family support, and primary care utilization were associated with cessation. Lower QoL and higher mood disturbances were associated with chronic stress. Predictor variables were independent (p ≤ .001) from BMI, but moderated by sex and SES.Conclusions
Policy-based strategy in public health should consider how preventive interventions may better accommodate different individual states and life situations, which could influence intervention completion. Intervention designs should enable in-built flexibility in delivery enabling response to individual needs.Trial registration
ClinicalTrials.gov Identifier: NCT01777893.
SUBMITTER: Huttunen-Lenz M
PROVIDER: S-EPMC10466828 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature

Huttunen-Lenz Maija M Raben Anne A Adam Tanja T Macdonald Ian I Taylor Moira A MA Stratton Gareth G Mackintosh Kelly K Martinez J Alfredo JA Handjieva-Darlenska Teodora T Bogdanov Georgi Assenov GA Poppitt Sally D SD Silvestre Marta P MP Fogelholm Mikael M Jalo Elli E Brand-Miller Jennie J Muirhead Roslyn R Schlicht Wolfgang W
BMC public health 20230830 1
<h4>Background</h4>Sedentary lifestyle and unhealthy diet combined with overweight are risk factors for type 2 diabetes (T2D). Lifestyle interventions with weight-loss are effective in T2D-prevention, but unsuccessful completion and chronic stress may hinder efficacy. Determinants of chronic stress and premature cessation at the start of the 3-year PREVIEW study were examined.<h4>Methods</h4>Baseline Quality of Life (QoL), social support, primary care utilization, and mood were examined as predi ...[more]