At admission hemodynamic instability is associated with increased mortality and rebleeding rate in acute gastrointestinal bleeding: a systematic review and meta-analysis.

ABSTRACT:

Background

Acute gastrointestinal bleeding (GIB) is a life-threatening event. Around 20-30% of patients with GIB will develop hemodynamic instability (HI).

Objectives

We aimed to quantify HI as a risk factor for the development of relevant end points in acute GIB.

Design

A systematic search was conducted in three medical databases in October 2021.

Data sources and methods

Studies of GIB patients detailing HI as a risk factor for the investigated outcomes were selected. For the overall results, pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated based on a random-effects model. Subgroups were formed based on the source of bleeding. The Quality of Prognostic Studies tool was used to assess the risk of bias.

Results

A total of 62 st

SUBMITTER: Tari E 

PROVIDER: S-EPMC10467304 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature