Understanding the effects of cortical gyrification in tACS: insights from experiments and computational models.

ABSTRACT: The alpha rhythm is often associated with relaxed wakefulness or idling and is altered by various factors. Abnormalities in the alpha rhythm have been linked to several neurological and psychiatric disorders, including Alzheimer's disease. Transcranial alternating current stimulation (tACS) has been proposed as a potential tool to restore a disrupted alpha rhythm in the brain by stimulating at the individual alpha frequency (IAF), although some research has produced contradictory results. In this study, we applied an IAF-tACS protocol over parieto-occipital areas to a sample of healthy subjects and measured its effects over the power spectra. Additionally, we used computational models to get a deeper understanding of the results observed in the experiment. Both experimental and numerical r

SUBMITTER: Cabrera-Alvarez J 

PROVIDER: S-EPMC10467425 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature