Acute heart failure in elderly patients admitted to the emergency department with acute dyspnea: a multimarker approach diagnostic study.

ABSTRACT:

Background and importance

Diagnosing acute heart failure (AHF) is difficult in elderly patients presenting with acute dyspnea to the emergency department.

Objectives

To assess the diagnostic accuracy of NT-proBNP, high-sensitivity cardiac troponin-I (Hs-cTnI), soluble ST2 (ST2), galectin-3 and CD146 alone and in combination for diagnosing AHF in elderly patients presenting with acute dyspnea to the emergency department.

Design, settings and participants

This was a prospective, multicenter study performed between September 2016 and January 2020, including elderly patients presenting with acute dyspnea to the emergency department of 6 French hospitals.

Intervention

Measurement of NT-proBNP, hs-cTnI, ST2, galectin-3 and CD146.

Outcome measure and analysis

T

SUBMITTER: Taheri O 

PROVIDER: S-EPMC10467808 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature