Neural similarity between overlapping events at learning differentially affects reinstatement across the cortex.

ABSTRACT: Episodic memory often involves high overlap between the actors, locations, and objects of everyday events. Under some circumstances, it may be beneficial to distinguish, or differentiate, neural representations of similar events to avoid interference at recall. Alternatively, forming overlapping representations of similar events, or integration, may aid recall by linking shared information between memories. It is currently unclear how the brain supports these seemingly conflicting functions of differentiation and integration. We used multivoxel pattern similarity analysis (MVPA) of fMRI data and neural-network analysis of visual similarity to examine how highly overlapping naturalistic events are encoded in patterns of cortical activity, and how the degree of differentiation versus integra

SUBMITTER: Hebscher M 

PROVIDER: S-EPMC10468827 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature